Life Cycle of Fasciola hepatica
Fasciola hepatica infects numerous mammals, especially cows, sheep and
other ruminants, existing in the bile passages of the liver. The egg
capsules are passed via bile to the small intestine, travel through the large
intestine to ultimately be deposited into the environment through feces.
Should the feces be deposited in water, the egg capsules will embryonate and in
about 9-10 days in warm weather, hatch, liberating the miracidium. This
ciliated, non-feeding larvae will seek out snails of Stagnicola bulimoides
or Fossaria modicella in the US but other related snails in other parts
of the world. Within the snail host, the miracidium transforms into a
sporocyst which in turn produces redia known as mother redia since they will
produce daughter redia. These intramolluscan stages will give rise to
cercaria of the gymnocephalus type which contain cystogenous glands that enable
them to form encysted metacercaria on vegetation or in the water. Should
the metacercaria-infected vegetation end up "high and dry" and be eaten or
should the host drink the metacercaria-contaminated water, these minute,
immature worms excyst in the small intestine, penetrate the lining of the
intestine and creep over internal organs till they find the liver. There
the young worms will invade the capsule of the liver and wander about through
the hepatic cells, feeding and growing until they enter the bile ducts about 2
months post-infection. About one month after entering the liver, the worms
attain adulthood and begin producing egg capsules.